Liquid chromatography / Mass Spectroscopy (LC / MS) is a technique which combines high-performance liquid chromatography HPLC, a powerful analytical separation technique with mass spectroscopy, a powerful analysis & detection technique. There are two common atmospheric pressure ionization (API) LC/MS processes: Electrospray Ionization (ESI) & Atmospheric Pressure Chemical Ionization (APCI). Both are soft ionization techniques. API processes are also compatible with most mobile phase solvents (volatile) & volatile buffers.
LC separations are detected by PDA & Mass spectrometer as different detectors.
Model: LCMS 8045
Brand: Shimadzu Scientific Instruments
Equipment Measurements & Capabilities:
| 1 | LC is combined with a Photo Diode Array detector (PDA). It has a three-dimensional projection over the entire UV-VIS range. It is a non-destructive detector so it can be put in series like LC-PDA Mass Spectrometer. |
| 2 | Ion Trap MS/MS Function: The LC is connected to MS and can be analyzed |
| 3 | Fastest scan speed (30,000 u/s) and polarity switching time (5 MS). |
| 4 | High-speed acquisition benefits the laboratory by reducing run times for increased throughput and also shortens method development time. |
Current Status of the Instrument : Under Maintenance
Location of the Instrument: Room No: 25, Ground Floor, Temporary Campus, IIT Palakkad